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Updated: Jun 16, 2026

Preparation and Characterization of Nanoliposomes for the Entrapment of Bioactive Hydrophilic Globular Proteins
Published on: August 31, 2019
Multicompartmental micro- and nanocapsules: hierarchy and applications in biosciences
Mihaela Delcea1, Alexey Yashchenok, Kristina Videnova
1Max-Planck Institute of Colloids and Interfaces, Research Park Golm, Potsdam 14424, Germany. mihaela.delcea@mpikg.mpg.de
Abstract:
Multicompartmentalized micro- and nanocapsules allow simultaneous delivery of several vectors or biomolecules; they are the next generation of carriers with increased complexity. Here we overview multicompartment micro- and nanocapsules and present a road-map for future developments in the field. Four basic building block structures are demonstrated, three isotropic: concentric, pericentric, and innercentric, and one anisotropic: acentric. As an elaborate implementation of multicompartmentalization, an enzyme-catalyzed reaction inside the same capsule carrying both an enzyme and a substrate is shown. Applications of multicompartmentalized microcapsules for simultaneous multiple drug delivery in bio-medicine are discussed.
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