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Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
Published on: August 15, 2016
Supramolecular Cyclodextrin Nanofibers for Active Food Preservation: Current Trends and Future Perspectives
Rajaram Rajamohan1, Iruthayapandi Selestin Raja2
1School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Foods (Basel, Switzerland)
|August 13, 2026
Summary
Cyclodextrin-based supramolecular nanofibers offer advanced active food packaging by encapsulating bioactive compounds for enhanced preservation. These materials improve food safety and extend shelf life through controlled release of natural preservatives.
Area of Science:
- Materials Science
- Food Science
- Nanotechnology
Background:
- Cyclodextrin (CD)-based supramolecular nanofibers (NFs) integrate host-guest chemistry with nanofibrous architectures for active food packaging.
- CDs' unique structure facilitates encapsulation of bioactive compounds, enhancing their solubility, stability, and controlled release.
Purpose of the Study:
- To comprehensively review CD-based supramolecular nanofibers for food preservation.
- To analyze the relationship between fiber morphology, supramolecular interactions, and controlled release properties.
- To evaluate recent advancements and compare CD-NFs with other encapsulation technologies.
Main Methods:
- Review of molecular structure and inclusion complexation mechanisms of CDs.
- Analysis of polymer-assisted and polymer-free electrospinning strategies for NF fabrication.
- Critical summary of biodegradable polymers, hybrid NFs, and cyclodextrin-based metal-organic frameworks (CD-MOFs).
Main Results:
- CD-based NFs demonstrate significant improvements in antimicrobial, antioxidant, moisture management, and barrier properties.
- Biodegradable polymers and CD-MOFs enhance encapsulation efficiency and mechanical stability.
- Applications show extended shelf-life for various food products through sustained preservative delivery.
Conclusions:
- CD-based nanofibers represent a promising multifunctional material for active food packaging.
- Challenges in large-scale manufacturing, stability, and regulatory approval need addressing for commercialization.
- Future directions include smart packaging, stimuli-responsive systems, and sustainable industrial implementation.
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