Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 16, 2026

Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications

Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications

Published on: September 2, 2025

Repeat pap testing and colposcopic biopsies in the underserved.

Katrina F Trivers¹, Vicki B Benard, Christie R Eheman

¹From the Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.

Obstetrics and Gynecology

|February 20, 2010

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Increasing Colorectal Cancer Screening: A Systematic Economic Review of Patient Navigation Services.

American journal of preventive medicine·2025

Same author

Preferences Among U.S. Women for Cervical Cancer Screening with Self-Collected Specimens for Human Papillomavirus Testing.

Obstetrics and gynecology·2025

Same author

HPV vaccination among gay, bisexual, and other men who have sex with men aged 27-45 years in the United States is potentially Cost-saving.

Vaccine·2025

Same author

Patterns of Telehealth Use During Pregnancy and Postpartum Among Commercially Insured Women.

Journal of women's health (2002)·2025

Same author

Estimated health outcomes of breast cancer screening in the national breast and cervical cancer early detection program by race/ethnicity.

Cancer causes & control : CCC·2025

Same author

Annual Report to the Nation on the Status of Cancer, featuring state-level statistics after the onset of the COVID-19 pandemic.

Cancer·2025

Colposcopic biopsies are frequently performed on young women following cervical cancer screening. However, these biopsies may not efficiently detect serious disease, contradicting current follow-up guidelines.

Area of Science:

Gynecology
Oncology
Public Health

Background:

Cervical cancer screening aims to detect precancerous and cancerous lesions early.
The National Breast and Cervical Cancer Early Detection Program (NBCCEDP) serves a large population of women.
Understanding patterns of follow-up testing is crucial for optimizing screening protocols.

Purpose of the Study:

To quantify the rates of repeat Pap testing and colposcopic biopsies in the NBCCEDP.
To analyze demographic factors associated with receiving colposcopic biopsies versus repeat Pap tests.
To evaluate the positive predictive value of different cervical cancer diagnostic strategies.

Main Methods:

Analysis of data from 955,494 women in the NBCCEDP (2003-2006).
Estimation of age-standardized rates for repeat Pap tests and colposcopic biopsies.

Related Experiment Videos

Last Updated: Jun 16, 2026

Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications

Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications

Published on: September 2, 2025

Multivariable logistic regression to determine odds ratios for colposcopic biopsy receipt.

Calculation of positive predictive values for cervical intraepithelial neoplasia (CIN) 2 or worse.

Main Results:

Over 39,000 women had repeat Pap testing and over 53,000 had colposcopic biopsies.
Rates were 37.2/1,000 for repeat Pap tests and 39.3/1,000 for colposcopic biopsies.
Younger, Hispanic, and African-American women were more likely to undergo colposcopic biopsies.
Positive predictive values for colposcopic biopsy were 27% for ASC-H and 70% for HSIL/SCC.

Conclusions:

Colposcopic biopsies are common in young women post-Pap screening.
Biopsies may not be efficient for detecting serious disease, except in cases of severe Pap results.
Findings challenge current recommendations for less aggressive follow-up in young women.