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Updated: Jun 16, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Locoregional spread of cutaneous melanoma: sonography findings
Orlando Catalano1, Corrado Caracò, Nicola Mozzillo
1First Department of Radiology, National Cancer Institute, Fondazione G. Pascale, Via M. Semmola, I-80131, Naples, Italy.
Objective:
This article reviews various aspects of locoregional spread of malignant cutaneous melanoma, as imaged with gray-scale sonography and Doppler techniques. The scenarios illustrated include disease staging (primary melanoma, satellite metastasis, in-transit metastasis, and lymphadenopathies), sentinel lymph node biopsy procedure, patient follow-up, recurrence detection, cutaneous metastasis, and sonographically guided intervention.
Conclusion:
High-resolution sonography allows recognition of small, clinically-occult melanomatous foci. It plays a major role in locoregional staging and follow-up of patients with cutaneous melanoma.

