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Updated: Jun 16, 2026

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Clinical Application of Microscope-Assisted Minimally Invasive Anterior Lumbar Interbody Fusion
Published on: June 16, 2023
Minimally invasive atlantoaxial fusion
Langston T Holly1, Robert E Isaacs, Anthony K Frempong-Boadu
1Department of Neurosurgery, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA. lholly@mednet.ucla.edu
Neurosurgery
|February 23, 2010
Summary
Minimally invasive C1-C2 fusion is a feasible surgical technique for atlantoaxial fixation, offering solid fusion with no intraoperative complications. This approach may reduce approach-related morbidity compared to open procedures.
Area of Science:
- Neurosurgery
- Orthopedic Surgery
- Spinal Fusion
Background:
- C1-C2 fusion techniques have evolved from wiring to screw-rod systems.
- Minimally invasive surgery (MIS) represents the latest advancement in atlantoaxial fixation.
Observation:
- Six patients with C1-C2 fusion (5 Type II odontoid fractures, 1 os odontoideum) underwent MIS over two years.
- All patients received bilateral segmental atlantoaxial fixation via an expandable tubular retractor.
Findings:
- Mean follow-up was 32 months with no intraoperative complications and minimal blood loss (100 mL).
- Solid fusion was achieved in all patients, confirmed by dynamic studies and CT scans showing no hardware malposition.
Implications:
- MIS C1-C2 instrumentation is technically feasible.
- Long-term outcomes are anticipated to be similar to open procedures, with potentially reduced approach-related morbidity.

