Related Experiment Video
Updated: Jun 16, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Exploration of a cognitive model to predict post-traumatic stress symptoms following childbirth
Elizabeth Ford1, Susan Ayers, Robert Bradley
1University of Sussex, Brighton, UK. e.ford@qmul.ac.uk
Unlabelled:
Women can suffer from post-traumatic stress disorder (PTSD) following childbirth. This study investigated the application of a cognitive model to PTS symptoms following childbirth and explored the addition of social support to the model.
Methods:
Women (N=138) completed questionnaires in pregnancy, 3-weeks and 3-months after birth, measuring prior trauma, beliefs, and coping in pregnancy; and birth interventions, social support, post-traumatic cognitions, and PTS symptoms post-birth.
Results:
Using structural equation modeling, a cognitive model explained 23% of the variance in PTS symptoms 3-weeks postpartum. Three-months postpartum, the model explained only 9% of the variance in PTS symptoms. The addition of social support, partially mediated by post-traumatic cognitions, increased the variance to 16%.
Discussion:
Results suggest that a cognitive model accounts for early PTS symptoms after birth. Social support after birth increases the explanatory power of the model at 3 months. A test of the model on a larger sample is warranted.
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