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Synthesis, antibacterial and antifungal activities of some carbazole derivatives
Fei-Fei Zhang1, Lin-Ling Gan, Cheng-He Zhou
1School of Chemistry and Chemical Engineering, Southwest University, Chongqing, China.
Abstract:
A series of N-substituted carbazole derivatives were synthesized and evaluated for antibacterial and antifungal activities against Staphylococcus aureus, methicillin-resistant Staphylococcus aureus (MRSA), Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, Bacillus proteus, Candida albicans and Aspergillus fumigatus by two fold serial dilution technique. Some of the synthesized compounds displayed comparable or even better antibacterial and antifungal activities than reference drugs fluconazole, chloramphenicol and norfloxacin against tested strains.
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