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Related Experiment Video

Updated: Jun 15, 2026

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries
04:59

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Primary phakic deep sclerectomy augmented with mitomycin C: long-term outcomes.

Nitin Anand1, Ashish Kumar, Alok Gupta

  • 1Department of Ophthalmology, Calderdale and Huddersfield NHS Trust, Huddersfield Royal Infirmary, Huddersfield, UK. anand1604@gmail.com

Journal of Glaucoma
|February 25, 2010
PubMed
Summary
This summary is machine-generated.

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Deep sclerectomy with mitomycin C effectively lowers intraocular pressure in open-angle glaucoma patients. However, many patients require laser goniopuncture for sustained IOP control, and some experience complications.

Area of Science:

  • Ophthalmology
  • Glaucoma Surgery
  • Surgical Outcomes

Background:

  • Deep sclerectomy (DS) is a surgical procedure for glaucoma.
  • Mitomycin C is an adjunct used to enhance surgical outcomes.
  • Long-term data on DS with mitomycin C in primary phakic glaucoma is valuable.

Purpose of the Study:

  • To evaluate the long-term efficacy and safety of deep sclerectomy (DS) combined with intraoperative mitomycin C.
  • To assess intraocular pressure (IOP) reduction and the need for additional interventions.
  • To report complications associated with this surgical technique in eyes without prior surgery.

Main Methods:

  • A retrospective analysis of 194 eyes from 160 patients undergoing primary phakic DS with mitomycin C.
  • Data collected from August 2001 to April 2005.

Related Experiment Videos

Last Updated: Jun 15, 2026

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries
04:59

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

  • Mean follow-up of 48 months.

    • Main Results:

    • High probability of achieving target IOP (<19, <16, <13 mmHg) without medications at 1 and 3 years post-surgery.
    • 66% of eyes required Nd:YAG laser goniopuncture (LGP) by 3 years.
    • Complications included intraoperative perforations (14.4%), iris complications (27.8%), hypotonic maculopathy (1.5%), and infections (1.5%).

    Conclusions:

    • Mitomycin C-enhanced primary DS provides effective IOP reduction in phakic open-angle glaucoma.
    • Laser goniopuncture is frequently necessary for sustained IOP control after DS.
    • While effective, DS carries risks of bleb-related infections and hypotonic maculopathy.