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Updated: Jun 15, 2026
08:48
Identification of Neutrophil Extracellular Traps in Paraffin-Embedded Feline Arterial Thrombi using Immunofluorescence Microscopy
Published on: March 29, 2020
Feline infectious peritonitis.
Teresa Goodson1, Susan Randell, Lisa Moore
1Affiliated Veterinary Specialists, Maitland, Florida, USA.
Compendium (Yardley, PA)
|February 25, 2010
Summary
Feline infectious peritonitis (FIP) is a fatal feline disease caused by a mutated coronavirus. Diagnosis remains challenging, and current treatments offer limited success, making prevention crucial.
Area of Science:
- Veterinary Medicine
- Immunology
- Infectious Diseases
Background:
- Feline infectious peritonitis (FIP) is a severe and often fatal disease in cats.
- It stems from a mutated, highly contagious feline coronavirus.
- FIP is prevalent in indoor cats within multi-cat environments.
Purpose of the Study:
- To summarize the current understanding of Feline Infectious Peritonitis (FIP).
- To highlight the diagnostic challenges and limitations of current treatments for FIP.
- To emphasize the importance of preventative measures against FIP.
Main Methods:
- Review of existing literature on Feline Infectious Peritonitis.
- Analysis of the pathogenesis, diagnosis, and treatment of FIP.
- Discussion of epidemiological factors influencing FIP prevalence.
Main Results:
- FIP results from a complex interaction between the feline coronavirus and the host immune system, leading to disseminated vasculitis.
- Antemortem diagnosis of FIP is difficult, despite ongoing development of new tests.
- Current therapeutic strategies for FIP are primarily supportive and involve immunosuppression.
Conclusions:
- Effective prevention of FIP, primarily through minimizing exposure to the causative coronavirus, is paramount.
- Further research is needed to improve antemortem diagnostic accuracy for FIP.
- Development of more effective treatments for FIP is a critical unmet need in feline medicine.
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