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Safety first: Recognizing and managing the risks to child participants in magnetic resonance imaging research
Matthias H Schmidt1, Jocelyn Downie
1Department of Radiology, Dalhousie University, Halifax, Nova Scotia, Canada. mhschmid@dal.ca
Insights
Managing risks in advanced biomedical research, especially with infants, requires current knowledge. This article reviews pediatric magnetic resonance imaging research risks and suggests questions for institutional review boards and researchers to identify potential hazards.
Area of Science:
- Biomedical research ethics
- Pediatric imaging safety
Background:
- Advanced biomedical research presents unique risks.
- Research involving pediatric populations introduces additional complexities.
- Existing knowledge on pediatric magnetic resonance imaging (MRI) research risks requires updates.
Purpose of the Study:
- To review recent information on physical risks in pediatric MRI research.
- To identify current information gaps concerning these risks.
- To provide strategies for risk management and formulate key questions for institutional review boards (IRBs) and researchers.
Main Methods:
- Literature review focusing on recent data regarding pediatric MRI research.
- Analysis of identified risks and information gaps.
- Development of risk management strategies and guiding questions.
Main Results:
- Recent information on physical risks in pediatric MRI research is presented.
- Specific information gaps concerning pediatric MRI research safety are highlighted.
- Strategies and key questions for risk assessment and management are formulated.
Conclusions:
- Specialized knowledge is crucial for managing advanced biomedical research risks, particularly in pediatric populations.
- IRBs and researchers must proactively address identified risks and information gaps in pediatric MRI studies.
- Utilizing formulated questions can help uncover and mitigate potential hazards in pediatric research protocols.
Abstract:
Specialized and up-to-date knowledge is required to identify and manage the risks associated with advanced biomedical research. Additional complexities need to be considered when the research involves infants or young children. In this article, we focus on recent information about the physical risks of pediatric magnetic resonance imaging research and highlight information gaps. With an eye to assisting institutional review boards and researchers, we consider strategies for the management of these risks and formulate key questions aimed at exposing hidden hazards. Institutional review boards should ask these questions, and researchers should bear them in mind as they develop research protocols.
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