Related Experiment Video
Updated: Jun 10, 2026

Comparing Eye-tracking Data of Children with High-functioning ASD, Comorbid ADHD, and of a Control Watching Social Videos
Published on: December 7, 2018
Subtypes of aggression in children with attention deficit hyperactivity disorder: medication effects and comparison
Sara King1, Daniel A Waschbusch, William E Pelham
1Department of Pediatrics, Dalhousie University and IWK Health Centre, Halifax, Nova Scotia, Canada. sara.king@dal.ca
Insights
Stimulant medication may reduce aggressive behaviors in children with attention deficit hyperactivity disorder (ADHD). Children with ADHD on placebo showed more reactive and proactive aggression than controls.
Area of Science:
- Child Psychology
- Neurodevelopmental Disorders
- Behavioral Science
Background:
- Aggressive behavior is a significant concern in children.
- Attention deficit hyperactivity disorder (ADHD) is associated with behavioral challenges.
- Understanding the impact of medication on aggression in ADHD is crucial.
Purpose of the Study:
- To investigate the effects of stimulant medication on different types of aggressive behavior in children with ADHD.
- To compare aggression levels in children with ADHD on medication versus placebo, and with typically developing controls.
Main Methods:
- A laboratory provocation task was used to measure hostile, instrumental, reactive, and proactive aggression.
- Participants included children with ADHD on stimulant medication, children with ADHD on placebo, and a control group.
- Aggression was assessed following varying levels of provocation.
Main Results:
- Children with ADHD on placebo displayed higher proactive and reactive aggression after provocation compared to controls.
- Instrumental aggression decreased in controls, and hostile aggression decreased in the ADHD-placebo group.
- Both instrumental and hostile aggression significantly reduced in children with ADHD receiving stimulant medication.
Conclusions:
- Stimulant medication appears to effectively reduce both instrumental and hostile aggressive behaviors in children with ADHD.
- Children with ADHD, particularly when untreated (placebo), exhibit heightened reactive and proactive aggression.
- Further research can explore long-term effects and mechanisms of medication on aggression in ADHD.
Abstract:
We examined aggressive behavior in 6- to 12-year-old children, including 20 children with attention deficit hyperactivity disorder (ADHD) on stimulant medication, 19 children with ADHD on placebo (n = 19), and 32 controls. Children completed a laboratory provocation task designed to measure hostile, instrumental, reactive, and proactive aggression. Children in the ADHD-placebo group exhibited increased proactive and reactive aggression following high levels of provocation compared to controls. On the last trials, instrumental aggression dissipated for controls and hostile aggression dissipated for children in the ADHD-placebo group. Both instrumental and hostile aggression dissipated for children in the ADHD-medication group.
More Related Videos
05:48The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
Published on: June 12, 2020
10:02Event Related Potentials (ERPs) and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder (ADHD)
Published on: March 12, 2020
Related Concept Videos
Bullying
Antipsychotic Drugs: Typical and Atypical Agents
Autism Spectrum Disorder
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Attention-Deficit/Hyperactivity Disorder
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Oppositional Defiant Disorder
Diagnostic Criteria and...
Conduct Disorder