Related Experiment Video
Updated: Jun 15, 2026
06:23
The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
Published on: October 13, 2016
[MMSE for survival prognostics in dementia]
Sebastian Dirk Hötte1, Daniel Lankers, Sebastian Kissler
1Ernst-Moritz-Arndt-Universität Greifswald und LWL-Universitätsklinik Bochum der Ruhr-Universität Bochum.
Psychiatrische Praxis
|February 26, 2010
Summary
The Mini-Mental State Examination (MMSE) can predict dementia patient survival. Higher dementia severity and lower MMSE scores correlate with increased mortality risk, aiding care planning.
Area of Science:
- Gerontology
- Neurology
- Biostatistics
Context:
- Dementia poses a significant global health challenge, impacting patients, families, and healthcare systems.
- Accurate prognostic tools are crucial for managing dementia care and resource allocation.
Purpose:
- To evaluate the predictive capability of the Mini-Mental State Examination (MMSE) for dementia patient survival.
- To quantify the relationship between MMSE scores, dementia severity, and mortality risk.
Summary:
- An 8-year follow-up study involving 145 dementia outpatients utilized Kaplan-Meier and Cox-regression analyses.
- Results indicated a 36.2% increase in relative death risk per dementia severity level (mild/moderate/severe) (p=0.023).
- Each one-point decrease in MMSE score was associated with a 4.1% rise in relative death risk (p=0.005).
Impact:
- MMSE scores offer valuable prognostic information for dementia survival.
- Findings support the use of MMSE in counseling caregivers and informing socioeconomic management of dementia.
- This research aids in anticipating the long-term needs and outcomes for individuals with dementia.
Related Concept Videos
01:21Cancer Survival Analysis
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
01:22Dementia l: Introduction
Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...