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Updated: Jun 15, 2026

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
[Early interventricular septum rupture after systemic thrombolysis in a patient with STEMI]
Antonio Maglione1, Alberto Forni, Biagio Liccardo
1U.O.C. di Cardiologia, Fondazione Evangelica Betania, Napoli, Italy. maglion.ant@virgilio.it
Abstract:
Intraventricular septal rupture (ISR) is one of the most dreadful complications during AMI, requiring early diagnosis and urgent surgery. However, medical (90%) and surgical (50%) mortality remain elevated. We report a case of a 59 years old patient with infero-posterior AMI complicated by ISR after thrombolysis. Despite early recognition of this complication by trans-thoracic echocardiography at bedside and prompt surgical intervention the patient died on the second post-surgical day.
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