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Updated: Jun 15, 2026

Whole-Kidney Three-Dimensional Staining with CUBIC
Published on: July 18, 2022
[Epithelioid angiomyolipoma of the kidney]
Yoshiko Tokuyama1, Tetsuo Fujita, Takahiro Hirayama
1The Department of Urology, Sagamihara Kyodo Hospital.
Abstract:
A 50-year-old male was referred to our hospital for a left renal mass which was incidentally found during a medical check-up. Abdominal ultrasonography, computed tomography, and magnetic resonance imaging showed a weak enhancement tumor devoid of fat densities at the lower pole of the left kidney. Under the diagnosis of renal cell carcinoma, radical nephrectomy was performed. Histopathological examination revealed large epithelioid cells, and immunohistochemical staining showed strongly positive for HMB-45. The patient was diagnosed with epithelioid angiomyolipoma of the kidney. Epithelioid angiomyolipoma is a rare variant of angiomyolipoma, which is sometimes occurred aggressive clinical behavior. However, our case remains without evidence of recurrence or metastasis after radical nephrectomy, and showed relatively better prognosis than in previous reports.
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