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Updated: Jun 15, 2026

High-Density Lipoprotein-Specific Phospholipid Efflux Assay
Published on: September 30, 2025
Correlation study of pulmonary embolism and high-density lipoprotein cholesterol
YuPeng Wang1, Ping Wang, HongWei Li
1Department of Heart Center, Capital Medical University Affiliated Beijing Friendship Hospital, Beijing, China.
Background:
It is currently thought that pulmonary embolism and deep vein thrombosis are different manifestations of the same pathological process of venous thromboembolism. Venous thromboembolism has a negative correlation with high-density lipoprotein cholesterol.
Hypothesis:
Pulmonary embolism has a negative correlation with the level of high-density lipoprotein cholesterol.
Methods:
A total of 90 patients with pulmonary embolism, diagnosed and treated at a single center, were retrospectively analyzed for the present study. Among them were 57 cases of pulmonary arterial trunk embolism in group A and 33 cases of pulmonary arterial non-trunk embolism in group B.
Results:
The results showed that the level of high-density lipoprotein cholesterol decreased markedly in patients with pulmonary arterial trunk embolism as compared to those with pulmonary arterial non-trunk embolism. A stepwise logistic regression analysis was performed upon the relationship between pulmonary arterial trunk embolism and multiple factors. The results showed that a pulmonary arterial trunk embolism had a negative correlation with the level of high-density lipoprotein cholesterol and a positive correlation with triglyceride and high sensitivity C-reactive protein.
Conclusions:
Pulmonary arterial trunk embolism is negatively correlated with the level of high-density lipoprotein cholesterol.
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