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Related Experiment Video

Updated: Jun 15, 2026

Surgical Treatment of an Endolymphatic Sac Tumor

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

A patient with Lemierre syndrome.

Efthimia G Vargiami¹, E Farmaki, D Tasiopoulou

¹1st Pediatric Clinic, Aristotle University of Thessaloniki, Dorilaiou 3, Kalamaria, Thessaloniki, 55133, Greece. keva@med.auth.gr

European Journal of Pediatrics

|February 27, 2010

Summary

Lemierre syndrome, a severe complication of throat infections, can lead to dangerous septic thrombophlebitis. This case highlights a pediatric Lemierre syndrome caused by Abiotrophia defectiva, successfully treated with antibiotics and anticoagulation.

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Area of Science:

Infectious Diseases
Vascular Surgery
Pediatric Critical Care

Background:

Lemierre syndrome, or postanginal sepsis, is a rare but serious complication of oropharyngeal infections.
It is characterized by septic thrombophlebitis of the internal jugular vein and potential septicemia.
Prompt diagnosis and management are crucial due to the risk of metastatic infections.

Observation:

A previously healthy 12-year-old boy presented with Lemierre syndrome.
The condition was secondary to a subcutaneous neck abscess.
The causative agent identified was streptococci, specifically Abiotrophia defectiva.

Findings:

The patient developed metastatic sequelae, indicating systemic spread of infection.
Treatment involved a combination of antibiotics (clindamycin and vancomycin) and low molecular weight heparin.
The therapeutic regimen led to an uneventful recovery.

Implications:

This case underscores the importance of recognizing Lemierre syndrome in pediatric patients presenting with neck infections.
Early antibiotic and anticoagulant therapy can significantly improve outcomes.
Abiotrophia defectiva should be considered in the differential diagnosis of oropharyngeal infections leading to Lemierre syndrome.