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One-day bowel preparation with polyethylene glycol 3350: an effective regimen for colonoscopy in children

Tonya Adamiak1, Muhammad Altaf, Michael K Jensen

  • 1Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

Gastrointestinal Endoscopy
|March 2, 2010
PubMed

Insights

A 1-day polyethylene glycol (PEG) 3350 bowel preparation regimen is safe and effective for pediatric colonoscopies. This study found a 93% success rate, supporting its use in children.

Area of Science:

  • Pediatric Gastroenterology
  • Endoscopic Procedures

Background:

  • Polyethylene glycol (PEG) 3350 is a safe and effective agent for chronic constipation and 4-day bowel preparation in children.
  • A 1-day PEG 3350 regimen exists for adults, but pediatric data are absent.

Purpose of the Study:

  • To assess the safety and effectiveness of a 1-day PEG 3350 bowel preparation regimen in children undergoing colonoscopy.

Main Methods:

  • Retrospective review of medical records from a tertiary-care center in 2008.
  • Included patients were 18 years or younger who received the 1-day PEG 3350 regimen before colonoscopy.
  • Evaluated outcomes included adequate preparation, colonoscopy success, and factors influencing inadequate preparation.

Main Results:

  • The study included 272 pediatric patients (median age 13.7 years).
  • The 1-day PEG 3350 regimen was effective in 93% of cases (253 patients).
  • Colonoscopy success rates were not significantly affected by indication, age, or constipation history.

Conclusions:

  • The 1-day PEG 3350 bowel preparation regimen is a safe and effective option for pediatric colonoscopy.
  • This regimen should be considered for children requiring colonoscopy.
  • Further research may explore broader applications and long-term outcomes.
Abstract

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