Related Experiment Video
Updated: Jun 15, 2026
Human Blastocyst Biopsy and Vitrification
Published on: July 26, 2019
Relevance of the site of assisted hatching in thawed human blastocysts: a preliminary report
Hirotoshi Miyata1, Hidehiko Matsubayashi, Noriko Fukutomi
1Osaka New ART Clinic and New ART Research Center, Osaka, Japan.
Abstract:
Preliminary data from a prospective randomized study of assisted hatching (AH) of thawed human blastocysts demonstrated that the rate of complete hatching was significantly higher for AH performed near the inner cell mass (ICM) than for AH at the side opposite to the ICM. This suggests the existence of polarity in the hatching process in human blastocysts, which requires further evaluation.
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