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The Effect of Aging on Tissues

Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
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Related Experiment Video

Updated: Jun 15, 2026

Generation of Self-assembled Vascularized Human Skin Equivalents
09:04

Generation of Self-assembled Vascularized Human Skin Equivalents

Published on: February 12, 2021

Vitamins and photoaging: do scientific data support their use?

Jamie Zussman1, Jennifer Ahdout, Jenny Kim

  • 1Division of Dermatology, Department of Medicine, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, California, USA.

Journal of the American Academy of Dermatology
|March 2, 2010
PubMed
Summary

This review examines the scientific evidence for vitamins in skincare products to combat photoaging. It aims to help dermatologists counsel patients on the effectiveness of these popular antioxidant cosmeceuticals.

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Last Updated: Jun 15, 2026

Generation of Self-assembled Vascularized Human Skin Equivalents
09:04

Generation of Self-assembled Vascularized Human Skin Equivalents

Published on: February 12, 2021

Area of Science:

  • Dermatology
  • Cosmeceutical science
  • Nutritional science

Background:

  • The cosmeceutical industry is rapidly expanding, with many products claiming to reduce signs of photoaging.
  • Vitamins are frequently incorporated into skincare due to their perceived antioxidant benefits.
  • There is a need for evidence-based guidance on the efficacy of vitamin-containing cosmeceuticals.

Purpose of the Study:

  • To systematically review the scientific evidence supporting the use of oral and topical vitamins for mitigating photoaging.
  • To provide dermatologists with substantiated information for patient counseling on cosmeceutical claims.
  • To summarize the underlying mechanisms of skin aging due to sun exposure.

Main Methods:

  • Comprehensive literature search for studies on vitamins and photoaging.
  • Systematic examination of evidence for both oral and topical vitamin formulations.
  • Review of research on the pathogenesis of photoaging.

Main Results:

  • The review synthesizes existing research on the efficacy of vitamins in addressing photoaging.
  • Evidence supporting specific vitamin applications in skincare is evaluated.
  • The pathogenesis of sun-induced skin aging is briefly outlined.

Conclusions:

  • Dermatologists require robust scientific data to advise patients on the efficacy of vitamin-based cosmeceuticals.
  • Further research may be needed to fully validate the benefits of certain vitamin formulations.
  • Understanding the evidence base is crucial for informed patient care in dermatology.