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Related Experiment Video

Updated: Jun 15, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection

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Bowel preparation regimen for computed tomography colonography.

Carola Behrens¹, Richard Eddy, Giles Stevenson

¹Department of Radiology, Victoria Hospitals, Victoria, British Columbia, Canada.

Canadian Association of Radiologists Journal = Journal L'Association Canadienne Des Radiologistes

|March 2, 2010

Summary

A modified bowel preparation for computed tomography colonography significantly reduced residual "sticky coat" material on the colonic lining. This optimized imaging and may allow for same-day colonoscopy if needed.

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Area of Science:

Radiology
Gastroenterology

Background:

Effective bowel preparation is crucial for accurate computed tomography colonography (CTC).
Residual contrast and fecal material can obscure colonic pathology, impacting diagnostic yield.

Purpose of the Study:

To evaluate if a reduced oral contrast dose and altered timing improve colonic cleansing for CTC.
To assess the impact on residual material, specifically the problematic "sticky coat" phenomenon.

Main Methods:

Retrospective analysis of 40 patients undergoing CTC.
Comparison of a standard bowel preparation regimen versus a modified regimen (reduced dose, earlier administration).
Blinded assessment of residual material using a defined scoring system by three independent observers.

Main Results:

The modified regimen significantly reduced the "sticky coat" (P < .005).
No significant difference was observed in residual fluid.
A trend towards fewer stool masses was noted but did not reach statistical significance.

Conclusions:

A modified bowel preparation with lower contrast volumes and earlier administration effectively decreases adherent contrast and fecal matter.
This improved preparation enhances radiologic analysis and potentially enables same-day therapeutic interventions like colonoscopy.