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Updated: Jun 15, 2026

Modified Posterior Vertebral Column Resection for Patients with Thoracolumbar Kyphotic Deformity
Published on: September 16, 2022
Infantile developmental thoracolumbar kyphosis with segmental subluxation of the spine
1Scottish National Spine, Deformity Centre, Royal Hospital for Sick Children, Sciennes Road, Edinburgh EH9 1LF, UK. atsirikos@hotmail.com
Insights
This study identifies infantile developmental thoracolumbar kyphosis with segmental subluxation of the spine in children. Surgical fusion effectively corrected the deformity and improved vertebral anomalies.
Area of Science:
- Pediatric Orthopedics
- Spinal Deformity Research
- Developmental Pediatrics
Background:
- Progressive thoracolumbar kyphosis in infants can be associated with spinal instability.
- Segmental instability and vertebral anomalies may contribute to spinal deformities.
Purpose of the Study:
- To describe a specific type of infantile spinal deformity: developmental thoracolumbar kyphosis with segmental subluxation.
- To differentiate this condition from congenital spinal displacement.
- To report on the outcomes of surgical intervention for this condition.
Main Methods:
- Case series of five children presenting with thoracolumbar kyphosis.
- Radiographic evaluation of spinal alignment and vertebral morphology.
- Treatment via localized posterior spinal fusion.
Main Results:
- All patients showed progressive kyphosis over three months.
- Posterior spinal fusion led to gradual kyphosis correction and vertebral reconstitution.
- One patient required exploration for pseudarthrosis at nine months.
Conclusions:
- 'Infantile developmental thoracolumbar kyphosis with segmental subluxation of the spine' is a distinct developmental spinal deformity.
- Early surgical intervention with spinal fusion can yield favorable outcomes.
- This condition, if progressive, poses a risk of neurological compromise.
Abstract:
We report five children who presented at the mean age of 1.5 years (1.1 to 1.9) with a progressive thoracolumbar kyphosis associated with segmental instability and subluxation of the spine at the level above an anteriorly-wedged hypoplastic vertebra at L1 or L2. The spinal deformity appeared to be developmental and not congenital in origin. The anterior wedging of the vertebra may have been secondary to localised segmental instability and subsequent kyphotic deformity. We suggest the term 'infantile developmental thoracolumbar kyphosis with segmental subluxation of the spine' to differentiate this type of deformity from congenital displacement of the spine in which the congenital vertebral anomaly does not resolve. Infantile developmental kyphosis with segmental subluxation of the spine, if progressive, may carry the risk of neurological compromise. In all of our patients the kyphotic deformity progressed over a period of three months and all were treated by localised posterior spinal fusion. At a mean follow-up of 6.6 years (5.0 to 9.0), gradual correction of the kyphosis was seen on serial radiographs as well as reconstitution of the hypoplastic wedged vertebra to normality. Exploration of the arthrodesis was necessary at nine months in one patient who developed a pseudarthrosis.
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