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Catheter-directed thrombolysis with conventional aspiration thrombectomy for lower extremity deep vein thrombosis

Yong Sun Jeon1, Yong Han Yoon, Joung Ym Cho

  • 1Department of Radiology, Inha University Hospital, Incheon, Korea.

Yonsei Medical Journal
|March 2, 2010
PubMed

Insights

Catheter-directed thrombolysis using aspiration thrombectomy effectively treats deep vein thrombosis (DVT) in the legs, showing significant clinical improvement and satisfactory long-term outcomes for most patients.

Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Cardiovascular Medicine

Background:

  • Deep vein thrombosis (DVT) is a significant cause of morbidity.
  • Lower extremity DVT requires effective treatment to prevent complications like pulmonary embolism and post-thrombotic syndrome.

Purpose of the Study:

  • To evaluate treatment outcomes of catheter-directed thrombolysis with conventional aspiration thrombectomy for symptomatic lower extremity DVT.
  • To assess the efficacy and safety of this minimally invasive DVT treatment approach.

Main Methods:

  • Retrospective review of 74 patients undergoing catheter-directed thrombolysis with aspiration thrombectomy.
  • Placement of inferior vena cava (IVC) filters in 81% of patients to prevent pulmonary embolism.
  • Use of stenting and balloon angioplasty in 50% of patients for iliac vein compression.

Main Results:

  • 91% of patients experienced clinical improvement within 48 hours.
  • Follow-up venography showed complete or partial thrombus resolution in 90% of patients.
  • Post-thrombotic syndrome occurred in 38% of patients, and DVT recurrence in 8%.

Conclusions:

  • Catheter-directed thrombolysis with aspiration thrombectomy is an effective treatment for lower extremity DVT.
  • This method yields satisfactory clinical results and good thrombus resolution rates.
  • Further management may be needed for post-thrombotic syndrome and recurrence prevention.
Abstract

Keywords:
Thrombolysiscatheterdeep vein thrombosisthrombectomy

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