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Updated: Jun 15, 2026

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
Published on: March 1, 2024
[Fungal infections and nail psoriasis]
Laura Gheucă Solovăstru1, D Vâţă
1Disciplina de Dermatologie, Facultatea de Medicină, Universitatea de Medicină si Farmacie "Gr.T. Popa" Iaşi.
Abstract:
Onychomycosis and psoriasis are common diseases and it is possible that they coexist in the same patient. Psoriasis is a common cause of disturbance of the nail morphology. Nail disorders was reported in 10-80% of patients with psoriasis and may be associated with all clinical forms of disease. It has been suggested that the nail dystrophy in patients with psoriasis produce the lose of the natural protective barrier and increase vulnerability to fungal infections. But most authors report that in patients with psoriasis the prevalence of onychomycosis is no higher than in the general population. We conducted an observational analytical retrospective study of case report forms of patients with nail psoriasis hospitalized in Iasi Dermatology Clinic, 2004-2008. 360 patients were hospitalized with psoriasis. Of these 32 patients had nail disorders.
Insights
Nail psoriasis can lead to nail disorders, but the risk of fungal infection (onychomycosis) in these patients is not higher than in the general population. This study analyzed patients with nail psoriasis to assess this risk.
Area of Science:
- Dermatology
- Mycology
- Clinical Medicine
Context:
- Onychomycosis and psoriasis are common conditions that can affect the same patient.
- Psoriasis frequently causes nail morphology disturbances, with nail disorders reported in 10-80% of psoriasis patients.
- Nail dystrophy in psoriasis may compromise the natural protective barrier, potentially increasing susceptibility to fungal infections.
Purpose:
- To investigate the prevalence of onychomycosis in patients with nail psoriasis.
- To compare the incidence of onychomycosis in nail psoriasis patients to the general population.
Summary:
- An observational retrospective study analyzed 360 psoriasis patients hospitalized between 2004-2008.
- Of these, 32 patients presented with nail disorders.
- The study aimed to determine if nail psoriasis increases the risk of onychomycosis.
Impact:
- Findings contribute to understanding the relationship between psoriasis, nail changes, and fungal infections.
- Clarifies whether patients with nail psoriasis have a higher risk of onychomycosis.
- Informs clinical management and patient counseling regarding nail health in psoriasis.
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