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Identifying and correcting non-Markov states in peptide conformational dynamics

Dmitry Nerukh1, Christian H Jensen, Robert C Glen

  • 1Department of Chemistry, Unilever Centre for Molecular Sciences Informatics, Cambridge University, CB2 1EW Cambridge, United Kingdom. dn232@cam.ac.uk

The Journal of Chemical Physics
|March 3, 2010
PubMed
Summary

Protein dynamics are Markovian at longer timescales but lose this property at shorter timescales. This study reveals why, offering a method to redefine states for accurate Markovian analysis in protein conformational transitions.

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