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Updated: Jun 15, 2026

Fabricating a Kidney Cortex Extracellular Matrix-Derived Hydrogel
Published on: October 13, 2018
Banded collagen in the kidney with special reference to collagenofibrotic glomerulopathy
Shaila R Khubchandani1, Arun R Chitale, Swarnalata Gowrishankar
1Jaslok Hospital & Research Center, Bhatia Hospital, Mumbai, India. shailakhubchandani@yahoo.co.in
Background:
The normal glomerular basement membrane, composed of type IV collagen, plays an important function in the process of filtration. Rarely, type III, type I, or type V collagen is seen in the glomerulus, resulting in three different types of non-immune mediated glomerulopathies recognized thus far. These are characterized by deposition of banded collagen fibers in the glomerulus.
Methods:
The authors reviewed 4934 kidney biopsies submitted over the past 5 years. Five of these revealed the presence of banded collagen in the glomeruli.
Conclusion:
Combined clinical and ultrastructural examination has led to a definitive diagnosis. These diseases exhibit indolent progression and as yet do not have specific treatment.
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