Related Experiment Video

Updated: Jun 15, 2026

COVID-19 Seroprevalence Test for IgG Antibody Levels Among Healthy Donors Across Different Pandemic Phases in Jeddah
04:43

COVID-19 Seroprevalence Test for IgG Antibody Levels Among Healthy Donors Across Different Pandemic Phases in Jeddah

Published on: June 24, 2025

Detection of coronaviruses in children with acute gastroenteritis in Maddina, Saudi Arabia

A M Kheyami1, T Nakagomi, O Nakagomi

  • 1Division of Medical Microbiology, University of Liverpool, Daulby Street, Liverpool, UK.

Annals of Tropical Paediatrics
|March 4, 2010
PubMed

Insights

Coronaviruses are common in children with diarrhea in Saudi Arabia, particularly among outpatients. Further research is needed to understand their role in pediatric gastroenteritis.

Area of Science:

  • Pediatric Gastroenterology
  • Virology
  • Epidemiology

Background:

  • The role of coronaviruses in pediatric gastroenteritis remains unclear.
  • This study investigated coronavirus detection and epidemiology in children with acute gastroenteritis in Saudi Arabia.

Purpose of the Study:

  • To determine the prevalence of coronaviruses in children with acute gastroenteritis.
  • To describe the epidemiological features of coronavirus infections in this population.

Main Methods:

  • Stool specimens were collected from children under 5 years old (April 2004-April 2005).
  • Children were either hospitalized or received outpatient oral rehydration therapy.
  • Coronaviruses were identified using electron microscopy.

Main Results:

  • Coronaviruses were detected in 6% (63/984) of children with acute gastroenteritis.
  • Detection rates were higher in outpatients (11%) than inpatients (3%).
  • Infections occurred year-round, peaking in late winter, with a median age of 42 months.

Conclusions:

  • Coronaviruses are frequently found in children experiencing diarrhea in Saudi Arabia.
  • The specific contribution of coronaviruses to pediatric gastroenteritis requires additional investigation.
Abstract

More Related Videos

Detection and Genogrouping of Noroviruses from Children's Stools By Taqman One-step RT-PCR15:16

Detection and Genogrouping of Noroviruses from Children's Stools By Taqman One-step RT-PCR

Published on: July 22, 2012

Development of Multiplex Real-Time RT-qPCR Assays for the Detection of SARS-CoV-2, Influenza A/B, and MERS-CoV03:53

Development of Multiplex Real-Time RT-qPCR Assays for the Detection of SARS-CoV-2, Influenza A/B, and MERS-CoV

Published on: November 10, 2023

Related Concept Videos

Bacterial Gastroenteritis01:18

Bacterial Gastroenteritis

Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...
Respiratory Syncytial Virus Disease01:29

Respiratory Syncytial Virus Disease

Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
Investigation of Disease Outbreaks01:23

Investigation of Disease Outbreaks

Multistate foodborne outbreaks pose significant public health risks and require meticulous investigation to identify sources and implement control measures. The Centers for Disease Control and Prevention (CDC) utilizes a dynamic seven-step process for these investigations, integrating data from laboratories, interviews, and environmental assessments to protect public health.Outbreak Detection: The detection of multistate outbreaks typically begins with PulseNet, the CDC's national laboratory...
Rapid Identification of Pathogens01:25

Rapid Identification of Pathogens

MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...