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Updated: Jun 15, 2026

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The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
Published on: August 2, 2017
[Placental parameters and fetal outcome].
Summary
Examining the placenta can reveal pregnancy complications linked to developmental disorders. Histologic analysis connects placental issues to preterm birth, stillbirth, and neonatal death, highlighting the importance of careful placental examination.
Area of Science:
- Perinatology
- Pathology
- Developmental Neuroscience
Context:
- Pregnancy complications can have long-term effects on infant development.
- Placental examination is crucial for understanding pregnancy outcomes.
- Limited epidemiologic data exists on placental abnormalities and adverse newborn outcomes.
Purpose:
- To review common placental findings and their association with clinical data and fetal outcomes.
- To emphasize the significance of thorough placental examination in clinical practice.
- To provide insights into the pathogenesis of developmental disorders through placental pathology.
Summary:
- Histologic examination of the placenta reveals strong links between placental findings and adverse pregnancy outcomes such as preterm delivery, stillbirth, and neonatal death.
- Placental abnormalities are associated with hypoxic problems and can offer insights into the etiology of neurologic and developmental disorders.
- This review highlights common placental findings, their clinical relevance, and impact on fetal development.
Impact:
- Highlights the diagnostic and prognostic value of placental examination in identifying pregnancy complications.
- Underscores the role of placental pathology in understanding the origins of neonatal and developmental disorders.
- Emphasizes the need for integrating detailed placental examination into routine obstetric and neonatal care for improved infant outcomes.
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