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Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
[Placental chorangiosis associated with abruption and hypoxia]
Chorangiosis is a rare abnormality of placental capillary proliferation, associated with hypoxia in utero. A 23-year-old primigravida developed placental abruption at 33 weeks' gestation, and an emergency cesarean section was performed. Placental histology revealed chorangiosis. The infant was in critical state and died on the next day. Our case confirms that perinatal mortality can be associated with chorangiosis. This diagnosis should be considered especially when no other significant obstetric incident is identified. Placentas should be monitored for placental abruption, a known consequence of chorangiosis.
Chorangiosis is a rare abnormality of placental capillary proliferation, associated with hypoxia in utero. A 23-year-old primigravida developed placental abruption at 33 weeks' gestation, and an emergency cesarean section was performed. Placental histology revealed chorangiosis. The infant was in critical state and died on the next day. Our case confirms that perinatal mortality can be associated with chorangiosis. This diagnosis should be considered especially when no other significant obstetric incident is identified. Placentas should be monitored for placental abruption, a known consequence of chorangiosis.
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