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Dual selectivity expressed in [2 + 2 + 1] dynamic clipping of unsymmetrical [2]catenanes
Gayane Koshkakaryan1, Dennis Cao, Liana M Klivansky
1The Molecular Foundry and the Advanced Light Source, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.
Abstract:
A pi-templated dynamic [2 + 2 + 1] clipping protocol is established for the synthesis of [2]catenanes from two parts dialdehyde, two parts diamine, and one part tetracationic cyclophane. It is further diversified for the selective formation of an unsymmetrical [2]catenane showing great translational selectivity by employing two different dialdehydes in a one-pot reaction. The dual selectivity and the dynamic nature are verified by (1)H NMR spectroscopy, X-ray single-crystal structural studies, and exchange experiments.
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