Persistent agmination of lymphomatoid papulosis
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Updated: Jun 15, 2026

Microscopic Observation of Lymphocyte Dynamics in Rat Peyer's Patches
Published on: June 25, 2020
Antonio Torrelo1, Isabel Colmenero, Angela Hernández
1Department of Dermatology, Hospital del Niño Jesús, 28009 Madrid, Spain. atorrelo@aedv.es
Abstract:
A 12-year-old boy had lesions clinically and histopathologically consistent with lymphomatoid papulosis (LP) which were persistent and appeared grouped in a circumscribed area of normal looking background skin on the right abdomen. Staging work-up did not disclose systemic disease. Persistent agmination of lymphomatoid papulosis (PALP) is somewhat different from classical LP because it involves a circumscribed, patch-sized area of the skin and the papules within never resolve completely despite some waxing and waning. PALP might be considered a localized or regional form of LP or a distinct lymphoproliferative disorder; in any case, at least a cautious long-term follow up is recommended, with attention to the possible development of true lymphoma.
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