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Related Concept Videos

Nucleic Acids and Nucleotides01:20

Nucleic Acids and Nucleotides

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and have instructions for its functioning. The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA).
Deoxyribonucleic Acid (DNA)
DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and the organelles such as chloroplasts and mitochondria. In...
Nucleic acids02:43

Nucleic acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...
Nucleic Acids02:43

Nucleic Acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...
Nucleic Acids02:43

Nucleic Acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...
Nucleic Acids02:43

Nucleic Acids

Nucleic acids are the most important macromolecules for the continuity of life. They carry the cell's genetic blueprint and carry instructions for its functioning.
DNA and RNA
The two main types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). DNA is the genetic material in all living organisms, ranging from single-celled bacteria to multicellular mammals. It is in the nucleus of eukaryotes and in the organelles, chloroplasts, and mitochondria. In prokaryotes, the...
IUPAC Nomenclature of Carboxylic Acids01:16

IUPAC Nomenclature of Carboxylic Acids

IUPAC names of carboxylic acids are systematically derived following a few rules discussed below.
For acyclic saturated monocarboxylic acids, the longest hydrocarbon chain containing the –COOH carbon is identified as the parent chain. Then, the last -e of the parent hydrocarbon name is replaced with a suffix -oic acid.

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Related Experiment Video

Updated: Jun 15, 2026

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
11:37

Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

Published on: July 28, 2017

An extended IUPAC nomenclature code for polymorphic nucleic acids.

Andrew D Johnson

    Bioinformatics (Oxford, England)
    |March 6, 2010
    PubMed
    Summary
    This summary is machine-generated.

    A new informatics code extends the International Union of Pure and Applied Chemistry (IUPAC) nomenclature to represent relative abundance in polymorphic nucleic acids. This system aids in managing human genetic variation data.

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    Related Experiment Videos

    Last Updated: Jun 15, 2026

    Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism
    11:37

    Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

    Published on: July 28, 2017

    Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
    15:22

    Nucleoside Triphosphates - From Synthesis to Biochemical Characterization

    Published on: April 3, 2014

    Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
    09:04

    Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

    Published on: September 21, 2017

    Area of Science:

    • Bioinformatics
    • Genomics
    • Molecular Biology

    Background:

    • The International Union of Pure and Applied Chemistry (IUPAC) established a nomenclature for incompletely specified nucleic acids 25 years ago.
    • Current informatics systems lack a standardized method to represent the relative abundance of polymorphic nucleic acids, such as single nucleotide polymorphisms (SNPs), within a single character or string.
    • This limitation hinders the comprehensive analysis of genetic variation data.

    Discussion:

    • This study proposes a novel informatics code as a direct extension of the existing IUPAC nomenclature.
    • The proposed code enables the representation of relative abundance for polymorphic nucleic acids.
    • Potential applications and limitations of this extended nomenclature are discussed.

    Key Insights:

    • A new informatics code is introduced to represent the relative abundance of polymorphic nucleic acids.
    • This code naturally extends the established IUPAC nomenclature system.
    • The primary application is to facilitate the representation of human genetic variation data.

    Outlook:

    • The proposed code is expected to assist in managing the growing volume of human genetic variation information.
    • Further development and validation of the code will be crucial for its widespread adoption.
    • This advancement could streamline research in population genetics and personalized medicine.