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Updated: Jun 15, 2026

Antigenic Liposomes for Generation of Disease-specific Antibodies
Published on: October 25, 2018
CD40mAb adjuvant induces a rapid antibody response that may be beneficial in post-exposure prophylaxis
Vijay Ns Bhagawati-Prasad1, Evy De Leenheer1, Nadine P Keefe1
1Department of Infection and Immunity, University of Sheffield Medical School, Beech Hill Rd, Sheffield S10 2RX, UK.
Abstract:
Active vaccination can be effective as a post-exposure prophylaxis, but the rapidity of the immune response induced, relative to the incubation time of the pathogen, is critical. We show here that CD40mAb conjugated to antigen induces a more rapid specific antibody response than currently used immunological adjuvants, alum and monophosphoryl lipid A.
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