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Related Concept Videos

Organization of the Brain01:30

Organization of the Brain

The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
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Lobes of the Cerebrum

The cerebral cortex, a critical structure of the brain, is intricately divided into two hemispheres, each consisting of four distinct lobes: occipital, temporal, frontal, and parietal. These lobes function cooperatively to regulate various cognitive and sensory functions, forming the basis of our complex neural capabilities.
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Updated: Jun 15, 2026

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions
08:06

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions

Published on: February 15, 2021

Two views of brain function.

Marcus E Raichle1

  • 1Departments of Radiology, Neurology, Neurobiology and Biomedical Engineering, Washington University School of Medicine, 4525 Scott Avenue, Room 2116, St Louis, MO 63110, USA. marc@npg.wustl.edu <marc@npg.wustl.edu>

Trends in Cognitive Sciences
|March 9, 2010
PubMed
Summary
This summary is machine-generated.

Brain function is primarily intrinsic, not just reactive to tasks. Understanding this internal processing is key to interpreting environmental demands and predicting future events, aligning with the brain's energy usage.

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Last Updated: Jun 15, 2026

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Area of Science:

  • Neuroscience
  • Cognitive Science
  • Systems Neuroscience
  • Cellular Neuroscience
  • Molecular Neuroscience

Background:

  • Traditional studies of brain function emphasize task-evoked responses, promoting a reflexive model.
  • This reflexive view, while productive, may overlook the brain's intrinsic processing capabilities.

Purpose of the Study:

  • To argue that brain function is predominantly intrinsic.
  • To highlight the role of intrinsic activity in interpreting, responding to, and predicting environmental demands.
  • To connect intrinsic brain activity with the allocation of the brain's energy resources.

Main Methods:

  • Conceptual argument integrating existing knowledge from various neuroscience fields.
  • Analysis of brain function in relation to energy resource allocation.
  • Emphasis on the need for interdisciplinary integration.

Main Results:

  • The intrinsic view of brain function better explains the brain's continuous activity and energy expenditure.
  • Intrinsic processing is crucial for navigating complex environmental interactions.
  • The brain's energy resources are significantly allocated to intrinsic activities.

Conclusions:

  • A paradigm shift towards understanding intrinsic brain activity is necessary.
  • Integrating cognitive, systems, cellular, and molecular neuroscience is vital for a comprehensive view.
  • Future research should focus on the dynamic interplay of molecular components driving intrinsic brain function.