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The SYBR Green I malaria drug sensitivity assay: performance in low parasitemia samples
Matthias G Vossen1, Sandra Pferschy, Peter Chiba
1Institute of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Kinderspitalgasse 15, A-1090 Vienna, Austria. matthias.vossen@meduniwien.ac.at
Abstract:
Validation of the sensitivity of the SYBR Green I in vitro test against an enzyme-linked immunosorbent assay (ELISA)-based drug sensitivity assay. Our results suggest that the SYBR Green I assay is a fast and inexpensive malaria drug screening assay for laboratory use. However, because of its lack of sensitivity in whole blood samples its usefulness for testing clinical samples may be limited.
