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N2-glucuronidation and N4-acetylation of sulphaphenazole by the turtle Pseudemys scripta elegans
T B Vree1, M L Vree, N Benneken Kolmer
1Department of Clinical Pharmacy, Sint Radboud Hospital, Nijmegen, The Netherlands.
The Veterinary Quarterly
|January 1, 1991
Abstract:
After an oral dose of 100 mg of sulphaphenazole, the turtle Pseudemys scripta elegans excretes 27% of the compound unchanged and 3.8% as N4-acetylsulphaphenazole. The expected glucuronide conjugate, sulphaphenazole-N2-glucuronide, is not formed and excreted.