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Updated: Jun 15, 2026

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
Published on: May 10, 2017
Use of botulinum toxin type A injection for neuropathic pain after trigeminal nerve injury
Seung Hyun Yoon1, Robert L Merrill, Jong Hoon Choi
1TMJ and Orofacial Pain Clinic, Department of Oral Medicine College of Dentistry, Yonsei University, Seoul, Korea.
Objective:
To present a case that neuropathic pain following traumatic injury of the inferior alveolar nerve, which was relieved by the injection of BTX-A.
Design:
Case report.
Setting:
Tertiary care University hospital.
Subject:
A 62-year-old female was referred by her general dentist to our clinic due to numbness and pain over the left side of her lower lip and chin region.
Intervention:
Botulinum toxin type A injected into the middle of chin area subcutaneously.
Results:
At 1 month after BTX-A injection, the affected area had decreased in size. And at 2 months, the patient reported a slight decreased in pain, and CPT differences being sustained at a reduced level.
Conclusions:
This case report suggests an effective new modality for treating neuropathic pain after trigeminal nerve injury. A further randomized controlled study involving a large number of patients is needed.

