Related Experiment Video
Updated: Jun 15, 2026

Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements
Published on: January 7, 2019
[A case of ketamine dependence]
Michał Błachut1, Katarzyna Sołowiów, Aleksandra Janus
1Oddział Kliniczny Psychiatrii Slaskiego Uniwersytetu Medycznego, Wielospecjalistyczny Szpital Powiatowy w Tarnowskich Górach.
This case study details a 52-year-old man with a 15-year ketamine dependence. The patient experienced psychological withdrawal symptoms like anxiety and sleep disturbances, but no physical ones, upon cessation.
Area of Science:
- Neuroscience
- Psychiatry
- Pharmacology
Background:
- Ketamine, an NMDA receptor antagonist and opiate receptor agonist, is a long-used anesthetic.
- Non-medical ketamine use has been documented since the 1960s.
- Psychiatric effects include agitation, hallucinations, stupor, and consciousness disorders.
Observation:
- A 52-year-old male presented with a 15-year history of ketamine dependence.
- The patient was admitted for treatment of withdrawal syndrome after abrupt discontinuation.
- Medical evaluation revealed ketamine dependence syndrome co-occurring with personality disorders.
Findings:
- No somatic withdrawal symptoms were observed.
- The patient reported psychological symptoms including anxiety and sleep disturbances.
- Treatment involved diazepam, carbamazepine, and vitamins, with patient motivation for cessation.
Implications:
- This case highlights the psychological aspects of ketamine withdrawal in long-term dependent individuals.
- Understanding these symptoms is crucial for effective treatment strategies.
- Further research can compare these findings with other documented ketamine abuse cases.
Related Concept Videos
Drug Dependence
Drug Abuse and Addiction: Pharmacological Phenomena
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Parenteral Anesthetics: Overview
Sedatives and Hypnotics Drugs: Barbiturates
Desensitization and Tachyphylaxis
Several...
