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Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

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Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
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Application of Hemostatic Devices in Laparoscopic Hepatectomy
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Published on: April 19, 2022

Topical hemostatic agents in otolaryngologic surgery.

Baran Acar1, Mehmet Ali Babademez, Hayriye Karabulut

  • 1Department of Otolaryngology, Keçiören Training and Research Hospital, Ankara, Turkey. drbaranacar@gmail.com

Kulak Burun Bogaz Ihtisas Dergisi : KBB = Journal of Ear, Nose, and Throat
|March 11, 2010
PubMed
Summary

Topical hemostatic agents control bleeding in ear, nose, and throat surgery. This review details their properties, actions, benefits, and complications, focusing on antigenic reactions.

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Area of Science:

  • Otolaryngology
  • Surgical Hemostasis
  • Biomaterials

Background:

  • Topical hemostatic agents are crucial for minimizing blood loss in otolaryngologic surgery.
  • Effective hemostasis improves surgical visualization and patient hemodynamic stability.
  • Complications often arise from antigenic reactions to hemostatic products.

Purpose of the Study:

  • To review traditional and novel topical hemostatic agents.
  • To analyze their chemical properties and mechanisms of action.
  • To evaluate the benefits and complications associated with their use.

Main Methods:

  • Literature review of topical hemostatic agents.
  • Classification based on mechanism of action (physical/mechanical).
  • Analysis of chemical properties, efficacy, and adverse events.

Main Results:

  • Topical agents are categorized by their hemostatic mechanisms.
  • Antigenic reactions represent a significant source of complications.
  • Both established and emerging agents are discussed regarding their profiles.

Conclusions:

  • Understanding agent properties is key to optimizing surgical outcomes.
  • Minimizing antigenic reactions is vital for patient safety.
  • This review provides a comprehensive overview for clinical application.