Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glycosaminoglycans01:23

Glycosaminoglycans

Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...
Proteoglycans01:05

Proteoglycans

Glycans, a class of complex heterogeneous molecules, can be covalently attached to proteins to form glycosylated proteins that regulate various physiological and pathological processes. Glycosylated proteins or glycoproteins comprise N-linked and O-linked oligosaccharides. O-glycosylation is the most common type of protein glycosylation. Here, glycans attach to the oxygen atom of the hydroxyl groups of Serine or Threonine residues. O-linked glycosylation occurs later in protein processing,...
Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Engineering biocompatible chitosan hydrogels with polyether-based crosslinkers for biomedical applications.

International journal of biological macromolecules·2026
Same author

Harnessing Supramolecular J-Aggregates in Deep Eutectic Solvents for Tunable NIR Photothermal and Photodynamic Therapy.

Nano letters·2026
Same author

Unveiling the chemical composition of a microbiota-derived extracellular polymeric substance and its antivirulence potential against Staphylococcus aureus from bovine mastitis.

Colloids and surfaces. B, Biointerfaces·2026
Same author

Eutectozymes as Soft Hybrid Materials for Advanced Biocatalysis.

Advanced materials (Deerfield Beach, Fla.)·2025
Same author

Surface functionalization of multilayer nanoparticles with hyaluronic acid or alternative polymers: Effects on cellular uptake and re-epithelialization in a human ex vivo wound model.

Carbohydrate polymers·2025
Same author

Terpene-Based Eutectic Solvent Microdroplets: A Strategy to Combat Antibiotic-Resistant <i>Helicobacter pylori</i>.

Langmuir : the ACS journal of surfaces and colloids·2025

Related Experiment Video

Updated: Jun 15, 2026

Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

Dendritic polyglycerols for biomedical applications.

Marcelo Calderón1, Mohiuddin Abdul Quadir, Sunil Kumar Sharma

  • 1Organic and Macromolecular Chemistry, Department of Chemistry and Biochemistry, Freie Universität Berlin, Takustrasse 3, 14195 Berlin, Germany.

Advanced Materials (Deerfield Beach, Fla.)
|March 11, 2010
PubMed
Summary
This summary is machine-generated.

Dendritic polyglycerols (PGs) are biocompatible, highly branched polymers with diverse biomedical applications. This review highlights their use in nanomedicine for drug delivery and regenerative medicine, focusing on antifouling surfaces.

More Related Videos

Electrospun Fibrous Scaffolds of Poly(glycerol-dodecanedioate) for Engineering Neural Tissues From Mouse Embryonic Stem Cells
08:03

Electrospun Fibrous Scaffolds of Poly(glycerol-dodecanedioate) for Engineering Neural Tissues From Mouse Embryonic Stem Cells

Published on: June 18, 2014

Generation and Recovery of &beta;-cell Spheroids From Step-growth PEG-peptide Hydrogels
09:21

Generation and Recovery of β-cell Spheroids From Step-growth PEG-peptide Hydrogels

Published on: December 6, 2012

Related Experiment Videos

Last Updated: Jun 15, 2026

Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

Electrospun Fibrous Scaffolds of Poly(glycerol-dodecanedioate) for Engineering Neural Tissues From Mouse Embryonic Stem Cells
08:03

Electrospun Fibrous Scaffolds of Poly(glycerol-dodecanedioate) for Engineering Neural Tissues From Mouse Embryonic Stem Cells

Published on: June 18, 2014

Generation and Recovery of &beta;-cell Spheroids From Step-growth PEG-peptide Hydrogels
09:21

Generation and Recovery of β-cell Spheroids From Step-growth PEG-peptide Hydrogels

Published on: December 6, 2012

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Polymer Chemistry

Background:

  • Nanomedicine requires biocompatible materials for drug delivery and antifouling surfaces.
  • Dendritic polymers offer unique, highly branched, and multifunctional structures.
  • Polyglycerols (PGs) are a promising class of dendritic polymers with established safety profiles.

Purpose of the Study:

  • To review the synthesis and biomedical applications of dendritic polyglycerols (PGs).
  • To highlight the potential of dendritic PGs in nanomedicine and regenerative medicine.
  • To focus on applications including drug, dye, and gene delivery, and non-fouling surfaces.

Main Methods:

  • Review of diverse syntheses of dendritic polyglycerols.
  • Analysis of biomedical applications based on existing literature.
  • Focus on properties like biocompatibility, chemical stability, and inertness.

Main Results:

  • Dendritic PGs exhibit excellent chemical stability and biocompatibility.
  • These polymers are suitable for drug, dye, and gene delivery systems.
  • Dendritic PGs can be utilized for creating non-fouling surfaces and matrix materials in regenerative medicine.

Conclusions:

  • Dendritic polyglycerols are versatile functional architectures for nanomedicine.
  • Their properties make them ideal candidates for advanced biomedical applications.
  • Further development of dendritic PGs holds significant promise for future medical innovations.