Related Experiment Videos
[Autoimmune thrombocitopenic purpura in pregnancy]
Akusherstvo I Ginekologiia
|March 16, 2010
Summary
Acquired autoimmune thrombocytopenic purpura (ATP) involves low platelet counts. Pregnancy with ATP requires careful monitoring and specialized medical teams, but termination is not medically indicated.
Area of Science:
- Hematology
- Obstetrics & Gynecology
- Immunology
Context:
- Acquired autoimmune thrombocytopenic purpura (ATP) is characterized by a significant decrease in platelet count due to premature destruction.
- Understanding the interplay between ATP and pregnancy is crucial for maternal and fetal well-being.
Purpose:
- To outline current views of hematologists and obstetricians on managing acquired ATP in children and adults.
- To address common questions regarding ATP, its correlation with pregnancy, symptoms, and effects on the autoimmune disease.
- To emphasize the importance of awareness regarding risks posed by ATP symptoms to both mother and fetus.
Summary:
- ATP involves a transient, acute, or chronic decrease in platelets (<50.109/l) from premature destruction.
- Pregnancy in women with ATP is generally permissible but necessitates enhanced monitoring and specialized therapeutic interventions.
- Optimal platelet count targets (80,000-100,000 ppm) are recommended near delivery, considering delivery method and anesthesia.
- Delivery management decisions should prioritize obstetrical considerations over ATP status.
Impact:
- Highlights the necessity of a collaborative approach involving obstetricians, hematologists, and pediatricians throughout pregnancy, delivery, and puerperium.
- Stresses that pregnancy termination is not medically supported for ATP.
- Underscores the need for cautious monitoring and treatment by a specialized medical team for pregnant women with ATP.
Related Concept Videos
01:24Disorders of Hemostasis
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
01:29Venous Thrombosis III: Interprofessional Care
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
01:30Anticoagulant Drugs: Low-Molecular-Weight Heparins
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
01:15Transcytosis of IgG
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...