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Infected urine as a risk factor for postprostatectomy wound infection
Infection Control and Hospital Epidemiology
|March 1, 1991
Summary
Preoperative urinary tract infections significantly increase the risk of postprostatectomy wound infections, even with antibiotic prophylaxis. Deferring elective prostatectomy until urine is sterile is recommended to reduce complications.
Area of Science:
- Urology
- Infectious Disease
- Surgical Outcomes
Background:
- Postprostatectomy wound infection is a significant complication.
- The role of preoperative urinary tract infection (UTI) in this complication requires further elucidation.
Purpose of the Study:
- To investigate the relationship between preoperative infected urine and the incidence of postprostatectomy wound infection.
- To compare this relationship in patients with and without indwelling urinary catheters.
Main Methods:
- A cohort of 150 patients undergoing open prostatectomy were assessed for preoperative urine infection and postoperative wound infection.
- Patients were stratified into groups with and without indwelling urinary catheters.
- All patients received antibiotic prophylaxis.
Main Results:
- A statistically significant increase in wound infection rates was observed in patients with preoperative infected urine (23.5%) compared to those with sterile urine (8.7%).
- This association persisted in both catheterized and non-catheterized patient groups.
- Identical organisms were recovered from wound and urine cultures in 84% of cases, suggesting a direct link.
Conclusions:
- Preoperative urinary infection is a direct risk factor for postprostatectomy wound infections.
- Elective prostatectomy should be postponed if urinary infection is present to minimize surgical site infections.