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Updated: Jun 15, 2026

Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli
Published on: September 25, 2016
Cerebral venous and dural sinus thrombosis* : state-of-the-art imaging
Jennifer Linn1, Hartmut Brückmann
1Department of Neuroradiology, University Hospital Munich, Munich, Germany, linn@nrad.de.
Insights
Cerebral venous and sinus thrombosis (CVST) is a rare stroke cause, primarily affecting young to middle-aged women. Early diagnosis is crucial due to variable symptoms, with imaging like MRI and CT aiding detection.
Area of Science:
- Neurology
- Radiology
Background:
- Cerebral venous and sinus thrombosis (CVST) is an uncommon yet significant cause of stroke.
- It affects all ages but predominantly young and middle-aged females.
- CVST presents with variable symptoms, often leading to diagnostic delays.
Purpose of the Study:
- To summarize the epidemiology, risk factors, clinical presentation, and prognosis of CVST.
- To review the neuroradiologic diagnostic methods for CVST.
- To evaluate the diagnostic utility of MRI, CT, and CTA in identifying CVST.
Main Methods:
- Literature review focusing on CVST epidemiology, clinical features, and prognosis.
- Analysis of neuroradiologic diagnostic modalities for CVST.
- Assessment of magnetic resonance imaging (MRI), computed tomography (CT), and CT angiography (CTA) in CVST diagnosis.
Main Results:
- CVST subtypes include sinus thrombosis (ST), deep cerebral venous thrombosis (DCVT), and cortical vein thrombosis (CVT).
- DCVT and CVT can occur in isolation or, more commonly, with ST.
- Diagnostic delay is frequent due to the wide spectrum of clinical symptoms.
Conclusions:
- CVST is a critical diagnosis in stroke patients, particularly in young and middle-aged women.
- Accurate and timely diagnosis relies heavily on advanced neuroradiologic techniques.
- Understanding the role of MRI, CT, and CTA is essential for effective CVST management.
Abstract:
Cerebral venous and sinus thrombosis (CVST) constitutes a rare but important cause of stroke. It occurs in all age groups, but affects predominately young and middle-aged females. Three subtypes of CVST can be differentiated: sinus thrombosis (ST), deep cerebral venous thrombosis (DCVT), and cortical vein thrombosis (CVT). Both DCVT and CVT can present either in isolated forms or - more often - in combination with an ST. The symptoms of CVST are highly variable, thus, diagnosis is often made with a considerable delay.This review first presents a short summary of the epidemiology, risk factors, clinical signs, and prognosis of CVST. Then, the authors focus on the neuroradiologic diagnosis of this disease, and give an overview of the diagnostic value of magnetic resonance imaging (MRI), computed tomography (CT), and CT angiography (CTA) for CVST.
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