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Updated: Jun 15, 2026

08:48
Neuronavigation-guided Repetitive Transcranial Magnetic Stimulation for Aphasia
Published on: May 6, 2016
Navigated transcranial magnetic stimulation
1Nexstim Ltd., Elimäenkatu 9 B, FI-00510 Helsinki, Finland. jarmo.ruohonen@nexstim.com <jarmo.ruohonen@nexstim.com>
Neurophysiologie Clinique = Clinical Neurophysiology
|March 17, 2010
Summary
Navigated transcranial magnetic stimulation (nTMS) offers causal mapping of brain activity, unlike other methods. This technique shows promise for clinical applications like presurgical mapping and stroke recovery.
Area of Science:
- Neuroscience
- Neurology
- Medical Imaging
Background:
- Transcranial magnetic stimulation (TMS) provides a unique method for non-invasive brain imaging.
- Unlike other techniques, TMS causally links stimulated cortical areas to physiological responses.
- Repetitive TMS (rTMS) has demonstrated potential therapeutic applications.
Purpose of the Study:
- To review the fundamental concepts of navigated TMS (nTMS).
- To evaluate factors influencing the accuracy and reproducibility of nTMS.
- To discuss nTMS advantages over functional MRI for motor cortex mapping.
Main Methods:
- Review of basic concepts behind navigated TMS.
- Evaluation of physical and physiological factors affecting nTMS accuracy and reproducibility.
- Discussion of nTMS applications and comparison with fMRI.
Main Results:
- TMS enables causal mapping of cortical areas, differentiating it from other imaging methods.
- Navigated TMS (nTMS) enhances accuracy and reproducibility for clinical applications.
- nTMS is effective for presurgical motor cortex mapping and stroke recovery assessment.
Conclusions:
- Navigated TMS is a valuable tool for precise, non-invasive brain mapping.
- Further development of nTMS protocols is crucial for widespread clinical adoption.
- nTMS shows significant potential in neurosurgery, depression therapy, and stroke rehabilitation.

