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Published on: November 4, 2010
Long-term maintenance of pediatric asthma: focus on budesonide/formoterol inhalation aerosol
Peter N Huynh1, Lyne G Scott, Kenny Yc Kwong
1Division of Allergy-Immunology, Department of Pediatrics, Los Angeles County, University of Southern California Medical Center, Los Angeles, CA, USA;
Insights
Current asthma guidelines emphasize achieving control in children. This review focuses on budesonide and formoterol, a safe and effective combination therapy for pediatric asthma management.
Area of Science:
- Pediatric Pulmonology
- Asthma Management
- Pharmacotherapy
Background:
- Asthma guidelines recommend treatment to achieve and maintain asthma control in children.
- Stricter recommendations exist for uncontrolled asthma to reduce morbidity and mortality.
- Newer combination agents offer improved safety and efficacy.
Purpose of the Study:
- To review the control of pediatric asthma.
- To focus on the use of budesonide in combination with formoterol.
- To highlight effective asthma management strategies for children.
Main Methods:
- Literature review of current asthma guidelines.
- Analysis of studies on combination inhaler therapies for pediatric asthma.
- Discussion of treatment adherence and co-morbidities.
Main Results:
- Budesonide and formoterol combination is safe and effective for pediatric asthma.
- Combination therapy, improved compliance, and co-morbidity management aid asthma control.
- Current guidelines support intensified therapy for uncontrolled pediatric asthma.
Conclusions:
- Budesonide and formoterol represent a valuable option for pediatric asthma control.
- Comprehensive management including controller agents and adherence is key.
- Adherence to guidelines can significantly improve outcomes in childhood asthma.
Abstract:
Current national and international asthma guidelines recommend treatment of children with asthma towards achieving and maintaining asthma control. These guidelines provide more stringent recommendations to increase therapy for patients with uncontrolled asthma in order to reduce asthma-related morbidity and mortality. Newer combination agents such as budesonide and formoterol have been shown to be safe and effective in treatment of asthma in children. Use of long-term controller agents like this in combination with improved compliance and treatment of co-morbid conditions have been successful in this endeavor. This review discusses control of pediatric asthma with focus on the use of budesonide in combination with formoterol.
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