[Application of static and dynamic light scattering--a review]

Dynamic light scattering (DLS) measures the oscillations of macromolecules (MM) (Brownian motion). Small MM move fast, large MM slowly. DLS allows one to measure the relaxation of the movements of these MM, together with their sizes and their hydrodynamic diffusion coefficients. By DLS not only the pathogenesis of a large number of eye diseases but also those of general diseases may be determined. The origin of this class of diseases is the condensation (agglutination) of MM. Medicaments, such as Panthetine, have been shown to be effective in animal experiments by acting on the ionic strength of disturbed MM. They may have a fair chance to be effective also in humans. Static light scattering (tyndallometry, nephelometry) (SLS) is able to determine the weight of MM, but however their shape, as DLS can.