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Pharmacogenetic influences on mycophenolate therapy.

Katherine A Barraclough1, Katie J Lee, Christine E Staatz

  • 1Department of Nephrology, Level 2, ARTS Building, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane, Qld 4102, Australia. katherine_barraclough@health.qld.gov.au

Pharmacogenomics
|March 19, 2010
PubMed
Summary

Genetic variations in drug-metabolizing enzymes and transporters significantly impact mycophenolic acid (MPA) therapy effectiveness in transplant patients. Understanding these single nucleotide polymorphisms (SNPs) is crucial for optimizing immunosuppression and patient outcomes.

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