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A unique bone-like variant of alkaline phosphatase
W E Schreiber1, T Gorecki, V Bernstein
1Department of Pathology, Vancouver General Hospital, British Columbia, Canada.
American Journal of Clinical Pathology
|May 1, 1991
Summary
Researchers identified a unique alkaline phosphatase (ALP) variant in a patient with prostate cancer. This unusual ALP isoenzyme exhibited altered properties after neuraminidase treatment, suggesting a bone origin.
Area of Science:
- Biochemistry
- Oncology
- Clinical Chemistry
Background:
- Elevated serum alkaline phosphatase (ALP) levels can indicate various conditions, including bone metastasis.
- Isoenzymes of ALP are crucial diagnostic markers, with specific forms linked to different tissues and diseases.