Steroid-resistant bullous pemphigoid treated with cyclosporin A

A 70-year-old woman with steroid-resistant bullous pemphigoid, severe osteoporosis, and several crush fractures was given cyclosporin A at a dose of 5 mg/kg/day. Considerable improvement was evident within 4 weeks, and control has been maintained over a period of 14 months allowing reduction of her steroid dose to 4 mg on alternate days.