Related Experiment Video

Updated: Jun 14, 2026

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
09:38

Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

Published on: April 14, 2016

An improved instrument for the determination of changes in the pain threshold caused by drugs

F B FLINN, A S CHAIKELIS

    The American Journal of Psychiatry
    |March 19, 2010
    PubMed
    Abstract

    No abstract available in PubMed .

    Keywords:
    ALGESIMETERSDRUGS/effectsINSTRUMENTSPAIN/threshold measurement

    More Related Videos

    Measuring Changes in Tactile Sensitivity in the Hind Paw of Mice Using an Electronic von Frey Apparatus
    07:49

    Measuring Changes in Tactile Sensitivity in the Hind Paw of Mice Using an Electronic von Frey Apparatus

    Published on: December 19, 2013

    Determining heat and mechanical pain threshold in inflamed skin of human subjects
    13:21

    Determining heat and mechanical pain threshold in inflamed skin of human subjects

    Published on: January 14, 2009

    Related Experiment Videos

    Last Updated: Jun 14, 2026

    Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery
    09:38

    Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery

    Published on: April 14, 2016

    Measuring Changes in Tactile Sensitivity in the Hind Paw of Mice Using an Electronic von Frey Apparatus
    07:49

    Measuring Changes in Tactile Sensitivity in the Hind Paw of Mice Using an Electronic von Frey Apparatus

    Published on: December 19, 2013

    Determining heat and mechanical pain threshold in inflamed skin of human subjects
    13:21

    Determining heat and mechanical pain threshold in inflamed skin of human subjects

    Published on: January 14, 2009

    Related Concept Videos

    Analgesia and Pain Management01:25

    Analgesia and Pain Management

    Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
    Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

    Opioid Analgesics: Synthetic and Semisynthetic Opioids

    Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...

    Articles linked to this work by shared authors, journal, and citation graph.

    A CHEMICAL AND PATHOLOGIC STUDY OF THE EFFECTS OF COPPER ON THE LIVER.

    The Journal of experimental medicine·2009

    Connectomic Determinants of Subcallosal Cingulate Deep Brain Stimulation for Depression.

    The American journal of psychiatry·2026

    Brain Stimulation Therapeutic Interventions in Neuropsychiatry: A Cambrian Explosion.

    The American journal of psychiatry·2026

    Artificial Intelligence as the Computational Framework for Adaptive Closed-Loop Neuromodulation in Psychiatry.

    The American journal of psychiatry·2026

    Shared Transcriptional Features of Layer 3 Pyramidal Neurons Projecting to the Monkey Dorsolateral Prefrontal Cortex.

    The American journal of psychiatry·2026

    National Trends in Benzodiazepine Dispensing.

    The American journal of psychiatry·2026

    Proteomic Signatures in Major Depressive Disorder and Depression Symptom Subtypes.

    The American journal of psychiatry·2026

    Phyto-Metabolomic Insights Into Ficus hispida Linn.: Antioxidant Activity, Polyphenolic Content, and Antidiabetic Marker Discovery via LC-ESI-Orbitrap-MS/MS and GC-QqQ-MS/MS.

    Journal of food science·2026

    Bavachin Attenuates Cognitive Impairment in Scopolamine-Induced Amnesia: Behavioral, Biochemical and Molecular Insights.

    Drug development research·2026

    Safety Assessment of Red Algae-Derived Ingredients as Used in Cosmetics.

    International journal of toxicology·2026

    Sesquiterpene synthases from Inonotus obliquus: functional characterization and β-farnesene production.

    Mycology·2026

    Case Report: Somatic GNAS and CACNA1D mutations responsible for adrenal cortisol-producing adenoma with multiple aldosterone-producing micronodules-concurrence of primary aldosteronism and mild autonomous cortisol secretion.

    Frontiers in medicine·2026

    Dissecting the mechanism of action of the adjuvant system AS01 in human immune cells: synergy of QS-21 and monophosphoryl lipid A and role of type I interferons.

    Frontiers in immunology·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us