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Ifosfamide-induced Fanconi's syndrome with growth failure in a 2-year-old child
J De Schepper1, G Stevens, M Verboven
1Departments of Pediatrics, V.U.B., Belgium.
The American Journal of Pediatric Hematology/Oncology
|January 1, 1991
Abstract:
Fanconi's syndrome with phosphopenic rickets is described in a 2-year-old girl who had been treated for an embryonal sarcoma with multiagent chemotherapy including high-dose ifosfamide. The radiological and biochemical signs of rickets disappeared after treatment with 25-OH vitamin D3 and phosphorus supplements. Monitoring of tubular function in children during and after treatment with ifosfamide is mandatory.